Tehran University of Medical Sciences Archives of Anesthesiology and Critical Care 2423-5849 0 0 2026 02 04 1377 1377 Sogol Asgari Department of Anesthesiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Seyed Sam Mehdi Hosseininasab Department of Anesthesiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Hasanali Ahmadi Department of Anesthesiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Faranak Behnaz Department of Anesthesiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. 2025 08 15 2025 09 01 Epidural steroid injection is an effective method for controlling spinal radicular pain. However, in elderly patients with a history of lumbar fusion surgery, anatomical changes can lead to complications such as headache, nausea, and vomiting after the injection. In this report, two patients, 70 and 75 years old, with a history of multilevel lumbar fusion surgery who developed these complications after epidural injection are presented. Conservative treatment, including furosemide and 3% hypertonic saline, was associated with complete improvement of symptoms. https://aacc.tums.ac.ir/index.php/aacc/article/view/1377