Tehran University of Medical Sciences Archives of Anesthesiology and Critical Care 2423-5849 0 0 2026 02 17 1432 1432 Muthia Sukma Department of Medical Study Program, Faculty of Medicine, Universitas Negeri Padang, Bukittinggi, Indonesia. Muhammad Syahrul Department of Medical Study Program, Faculty of Medicine, Universitas Andalas, Padang, Indonesia. Fuad Saddam Department of Medical Study Program, Faculty of Medicine, Universitas Negeri Padang, Bukittinggi, Indonesia. Flori Humani Department of Medical Study Program, Faculty of Medicine, Universitas Negeri Padang, Bukittinggi, Indonesia. Arzeta Aprillia Department of Medical Study Program, Faculty of Medicine, Universitas Negeri Padang, Bukittinggi, Indonesia. Adelia Khayla Edward Department of Medical Study Program, Faculty of Medicine, Universitas Negeri Padang, Bukittinggi, Indonesia. Rika Susanti Department of Medical Study Program, Faculty of Medicine, Universitas Andalas, Padang, Indonesia. 2025 10 01 2025 10 27 Background: The study aimed to examine the relationship between weekly working hours and burnout syndrome among operating room nurses, focusing on the three core dimensions of burnout: emotional exhaustion, depersonalization, and personal accomplishment. Methods: The study involved 121 operating room nurses at Dr. M. Djamil General Hospital, Padang. The data were gathered by means of the Maslach Burnout Inventory (MBI) and analyzed using Pearson Correlation and Multiple Linear Regression.   Results: Emotional exhaustion was significantly associated with burnout levels (p = 0.007), whereas depersonalization and personal accomplishment did not show statistically significant effects. A weak but significant negative correlation was identified between working hours and personal accomplishment (r = –0.183, p = 0.044). Conclusion: Emotional exhaustion emerged as the most influential factor in predicting burnout among operating room nurses. Emotional fatigue interventions and psychological support system reinforcement are suggested for reducing burnout risk among them. https://aacc.tums.ac.ir/index.php/aacc/article/view/1432