Tehran University of Medical Sciences Archives of Anesthesiology and Critical Care 2423-5849 7 3 2021 07 31 201 202 Ali Jabbari Ischemic Disorders Research Center of Golestan University of Medical Sciences and Department of Anesthesiology and Intensive Care Medicine, Golestan University of Medical sciences, Gorgan, Iran. Alireza Jahangirifard Lung Transplantation Research Center, National Research Institute of Tuberculosis and lung Disease, Shahid Beheshti University of Medical Sciences, Tehran, Iran. 2021 06 23 2021 07 06 Tramadol has a narcotic-like structure. It is a synthetic, centrally acting analgesic drug. Many drugs have been used to treat postanesthesia shivering. Actually, Tramadol is used to treat moderate to severe pain but it has been shown an anti-shivering effect in some setting.Tramadol is a weak opioid agonist and an inhibitor of monoamine neurotransmitter reuptake.It provided effective analgesia in children and adults for both inpatient and day surgery. Tramadol was generally well tolerated in the clinical setting but, we do not prescribe it for use in adult younger than 18 years old due to frequent adverse effect. Tramadol has not clinically relevant adverse effects on hemodynamic and cardiovascular or respiratory parameters at average dosage. Perioperative prescription of Tramadol could decrease postanesthesia shivering beside acceptable post-operation pain management and better patient well-being and satisfaction. https://aacc.tums.ac.ir/index.php/aacc/article/view/372