Tehran University of Medical Sciences Archives of Anesthesiology and Critical Care 2423-5849 8 3 2022 06 11 260 262 Surabhi Sandill Department of Anaesthesiology and Critical Care, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India. Bhavya Krishna Department of Anaesthesiology and Critical Care, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India. Santvana Kohli Department of Anaesthesiology and Critical Care, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India. Binita Jaiswal Department of Anaesthesiology and Critical Care, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India. 2021 11 22 2022 01 03 Superior vena cava (SVC) syndrome, a potentially life threatening medical emergency, occurs due to SVC obstruction caused by extrinsic compression, intrinsic stenosis or thrombosis.  Malignant mediastinal tumours account for more than 80% of cases of SVC syndrome. We hereby report a case of SVC syndrome who came with clinical features suggestive of SVC syndrome with dyspnea managed and diagnosed in the Intensive Care Unit with a multidisciplinary approach https://aacc.tums.ac.ir/index.php/aacc/article/view/444