Tehran University of Medical Sciences Archives of Anesthesiology and Critical Care 2423-5849 8 Supp. 1 2022 11 07 413 415 Çağla Yazar Başkent University Hospital, Department of Anesthesiology, Ankara, Turkey. Nursultan Akmatov Başkent University Hospital, Department of Anesthesiology, Ankara Coşkun Araz Başkent University Hospital, Department of Anesthesiology, Ankara, Turkey. Nedim Çekmen Başkent University Hospital, Department of Anesthesiology, Ankara, Turkey. 2022 03 02 2022 04 04 Plasminogen (PLG) is a serum protein, a precursor of plasmin, in addition to its functions in the coagulation pathway, it also plays an important role in wound healing. PLG deficiency is a rare condition and has been associated with pseudomembranous (ligneous) lesions on mucous membranes, for example: ligneous gingivitis, endometritis and mostly conjunctivitis in the literature. In our case, the patient was a 30-years-old pregnant woman who was diagnosed with PLG deficiency and was at 39+4 week of pregnancy. We chose the neuraxial anesthesia (NA) to avoid possible airway obstruction due to difficult intubation and mucosal damage of upper airways. So, we administered single shot atraumatic spinal anesthesia (SA) for emergency cesarean section (C/S). Herein, preoperative optimization, a good preliminary assessment and selection of the type of anesthesia are important in terms of preventing complications in these patients. https://aacc.tums.ac.ir/index.php/aacc/article/view/499