Tehran University of Medical Sciences Archives of Anesthesiology and Critical Care 2423-5849 9 4 2023 08 01 369 371 Jyoti Deshpande Department of Anesthesiology, SMCW, Symbiosis International University, Pune, India. Shreya Rawekar Department of Anesthesiology, Smt.Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India. 2022 07 06 2022 07 23 Osteogenesis Imperfecta is a collagen disorder of autosomal dominant type caused by mutation of type COLIA-1 and COLIA-2 genes. Orthopaedic surgery in paediatric patient patients of OI is challenging mainly due to difficult airway and risk of malignant hyperthermia. Here we report, a paediatric case of OI with similar family history posted for radius ulna nailing which was managed with total intravenous anaesthesia and supraclavicular brachial plexus block. https://aacc.tums.ac.ir/index.php/aacc/article/view/597