Tehran University of Medical Sciences Archives of Anesthesiology and Critical Care 2423-5849 2 3 2016 08 10 207 209 EN Sohrab Salimi Assistant Professor of Anesthesiology, Department of Anesthesiology and Critical Care, Emam Hussain Hospital, Shahid Beheshti University of Medical Sciences,Tehran, Iran Morteza Jabbari Moghaddam Assistant Professor of Anesthesiology, Department of Anesthesiology and Critical Care, Emam Hussain Hospital, Shahid Beheshti University of Medical Sciences,Tehran, Iran Noushin Khazaei Resident of Anesthesiology, Department of Anesthesiology and Critical Care, Emam Hussain Hospital, Shahid Beheshti University of Medical Sciences,Tehran, Iran Ali Movafegh Professor of Anesthesiology, Department of Anesthesiology and Critical Care,Dr. Shariati hospital, Tehran University of Medical Sciences, Tehran, Iran Omid Azimaraghi Assistant Professor of Anesthesiology, Department of Anesthesiology and Critical Care, Dr. Shariati hospital, Tehran University of Medical Sciences, Tehran, Iran Reza Atef Yekta Assistant Professor of Anesthesiology, Department of Anesthesiology and Critical Care, Dr. Shariati hospital, Tehran University of Medical Sciences, Tehran, Iran Alireza Saliminia Assistant Professor of Anesthesiology, Department of Anesthesiology and Critical Care, Dr. Shariati hospital, Tehran University of Medical Sciences, Tehran, Iran Seyed Sajjad Razavi Associate Professor of Anesthesia, Mofid Hospital, Shahid Beheshti Medical University, Tehran, Iran 2016 05 16 2016 06 13 Background: Hemodynamic instability is common during tracheal intubation. The primary purpose of the present study is to evaluate the effect of different doses of remifentanil added to propofol on the hemodynamic profiles during tracheal intubation. Methods: Ninety patients, 40 to 70 years old, undergoing coronary artery bypass graft surgery under general anesthesia were randomly allocated into control, low (2µg/kg) and high (4ug/kg) dose groups. Baseline heart rate (HR), mean arterial pressure (MAP) were recorded and documented again on intubation and 1, 2 and 4 minutes after intubation. Cough status before and after intubation was also recorded. Results: The basic characteristics of participants in all the three groups were similar. Heart rate and blood pressure decreased in all three groups after intubation. There was no difference in the intubation conditions and mask ventilation or coughing between the three groups. Conclusion: There was no significant difference observed between hemodynamic changes with high and low dose of remifentanil to attenuate the rise in MAP on intubation. https://aacc.tums.ac.ir/index.php/aacc/article/view/77 https://aacc.tums.ac.ir/index.php/aacc/article/download/77/212