Tehran University of Medical Sciences Archives of Anesthesiology and Critical Care 2423-5849 10 Supp. 1 2024 03 11 440 445 Faranak Behnaz Department of Anesthesiology, Anesthesiology Research Center, Shohada -e-Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Rahmatollah Mohammadzadeh Namaghi Department of Anesthesiology, Anesthesiology Research Center, Shohada -e-Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Gholmreza Mohseni Department of Anesthesiology, Anesthesiology Research Center, Shohada -e-Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Meisam Jafari Kafiabadi Department of Orthopedic Surgery, Clinical Research Center Development Unit of Shohada-e-Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. 2023 09 23 2023 10 09 Background: The purpose of this study is to investigate the rate of allogeneic transfusion after the administration of intravenous iron in patients who are candidates for intertrochanteric fracture surgery. Methods: Patients who were candidates for intertrochanteric surgery referred to the orthopedic surgery and trauma department of Shahada Tajrish Hospital were included in the study after providing full explanations and obtaining written consent. The 80 patients were randomly divided into control group (No: 40) and intervention (No: 40). Patients in the intervention group were prescribed 600 mg of Venofer drug by ViforCo. This is while patients in the control group were not injected with Venofer before surgery. The results were evaluated using t-test and SPSS21 software. Results: Based on the results, the 1 hour after surgery, three indicators of systolic blood pressure, pulse rate, breathing rate, RBC showed a significant decrease in patients undergoing intervention (P<0.05). However, the oxygenation index showed a significant increase in the patients of this group (P>0.05). Meanwhile, in the period of 1 week after the surgery, we also see a significant decrease in the two indices of average hemoglobin and PTT time in the mentioned patients compared to the control subjects (P=0.030, P=0.037). The amount of blood consumed significantly lower in the patients of the intervention group than in the control group. Conclusion: The administration of injectable iron in patients with intertrochanteric fracture surgery candidates can improve some of the patients' clinical indicators in addition to a significant reduction in allogeneic blood transfusion. https://aacc.tums.ac.ir/index.php/aacc/article/view/869