Epidemiology and Descriptive Analysis of Neuro-Critical Care Unit; Shiraz, South of Iran

  • Somayyeh Hasane Tamar Department of Neurology, Medical School, Shiraz University of Medical Sciences, Shiraz, Iran
  • Saeed Hoseini Hooshiar Department of Neurology, Medical School, Shiraz University of Medical Sciences, Shiraz, Iran
  • Sina Karamimagham Department of Pediatrics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Maryam Poursadeghfard Clinical Neurology Research Center, Department of Neurology,Medical School, Shiraz University of Medical Sciences, Shiraz, Iran
Keywords: neurointensive care unit, epidemiology, descriptive analysis


Background: Neurocritical Intensive Care Units (NICUs) have been provided as new sub-special intensive care wards to give more special services for patients with acute neurology problems. As we know, there is no organized database about epidemiology of NICU patients in our country. Population-based assessment (even in a small population) could be a starting point to achieve an insight about neuro-critical ill patients in our area.Methods: This study is a retrospective cross-sectional study. We included all patients admitted in our NICU, a subspecialty neurology center in the south of Iran. The patients' hospital charts were used for gathering data. SPSS version 18.0 (SPSS Inc, Chicago, Illinois) was used for statistical analysis.Results: From a total of 130 patients, 68 (52.3%) were male and 62 (47.7%) female. Their mean age was 53.7±18.9 years. CVA was the most common cause of ICU admission (50% of total patients) and status epilepticus was the least (8.5%). The discharge- death ratio was 2.6. 84 patients (64.6%) were admitted for less than 14 days and 46 (35.4%) for more than 14 days. 85 (65.4%) patients took ventilator support with the mean duration of 8.29±10 days.Conclusion: Our findings provide an introduction into NICU field in our area. It could help us asses the effectiveness of our health care system and may additionally serve new planning for future needs to improve our general and neuro-ICUs. However, much research with larger patients’ population is required for better definition of details.


Adhikari N, Fowler R, Bhagwanjee S, Rubenfeld G. Critical care and the global burden of critical illness in adults. Lancet. 2010; 375(9749):1339-46.

Vasilevskis EE, Kuzniewicz MW, Cason BA, Lane RK, Dean ML, Clay T, et al. Predictors of early postdischarge mortality in critically ill patients: a retrospective cohort study from the California Intensive Care Outcomes project. J Crit Care. 2011; 26(1):65-75.

Rincon F, Mayer SA. Neurocritical care: a distinct discipline? Curr Opin Crit Care. 2007; 13(2):115-21.

Howard R, Kullman D, Hirsch N. Admission To Neurological Intensive Care: Who, When, And Why? J Neurol Neurosurg Psychiatry. 2003;74:(Suppl III):iii2–iii9.

Lizana F, Bota D, De Cubber M, Vincent J. Long-term outcome in ICU patients: What about quality of life? Intensive Care Med. 2003; 29(8):1286-93.

Dragsted L, Qvist J. Epidemiology of intensive care. International Journal of Technology Assessment In Health Care. 1992; 8(3):395-407.

Martin G. Epidemiology studies in critical care. Crit Care. 2006; 10(2):136.

Fowler R, Sabur N, Li P, Juurlink D, Pinto R, Hladunewich MA, et al. Sex- and age-based differences in the delivery and outcomes of critical care. CMAJ. 2007; 177(12):1513-9.

Lipes J, Mardini L, Jayaraman D. Sex and Mortality of Hospitalized Adults After Admission to an Intensive Care Unit. Am J Crit Care. 2013; 22(4):314-9.

Laskou M, Katsiari M, Mainas E, Kotsaimani A, Karampela I, Magina A. ICU patients: does age make any difference? Critical Care. 2008; 12(Suppl 2):P496.

Lerolle N, Trinquart L, Bornstain C, Tadie JM, Imbert A, Diehl JL, et al. Increased intensity of treatment and decreased mortality in elderly patients in an intensive care unit over a decade. Crit Care Med. 2010; 38(1):59-64.

Ashjazadeh N, Borhani Haghighi A, Poursadeghfard M, Azin H. Cerebral venous-sinus thrombosis: a case series analysis. Iran J Med Sci. 2011; 36(3):178-82.

Im K, Belle SH, Schulz R, Mendelsohn AB, Chelluri L. Prevalence and outcomes of caregiving after prolonged (≥ 48 hours) mechanical ventilation in the icu. Chest. 2004; 125(2):597-606.

Mrozek S, Constantin JM, Geeraerts T. Brain-lung crosstalk: Implicationsand their outcome for neurocritical care patients. Brain-lung crosstalk: Implicationsand their outcome for neurocritical care patients. 2015; 4(3):163-78.

Wunsch H, Linde-Zwirble WT, Angus DC, Hartman ME, Milbrandt EB, Kahn JM. The epidemiology of mechanical ventilation use in the United States. Crit Care Med. 2010; 38(10):1947-53.

Esteban A, Anzueto A, Frutos F, Alía I, Brochard L, Stewart TE, et al. Characteristics and outcomes in adult patients receiving mechanical ventilation: A 28-day international study. JAMA. 2002; 287(3):345-55.

Asadzandi M, Taghizade Karati K, Tadrisi S, Ebadi A. Estimation of the mortality rate using the APACHE II standard disease severity scoring system in intensive care unit patients. Iranian Journal of Critical Care Nursing. 2012; 4(4):209-14.

Ala S, Pakravan N, Ahmadi M. Mortality Rate and Outcome among Patients Admitted to General Intensive Care Unit during “Morning-Hour” Compared with “Off-Hour”. International Journal of Clinical Medicine. 2012; 3:171-7.

Mayr VD, Dünser MW, Greil V, Jochberger S, Luckner G, Ulmer H, et al. Causes of death and determinantsof outcome in critically ill patients. Critical care. 2006; 10(6):R154.

Fakhry SM, Trask AL, Waller MA, Watts DD. Management of brain-injured patients by an evidence-based medicine protocol improves outcomes and decreases hospital charges. J Trauma. 2004; 56(3):492-9; discussion 499-500.

Patel HC, Menon DK, Tebbs S, Hawker R, Hutchinson PJ, Kirkpatrick PJ. Specialist neurocritical care and outcome from head injury. Intensive Care Med. 2002; 28(5):547-53.

Suarez JI. Outcome in neurocritical care: advances in monitoring and treatment and effect of a specialized neurocritical care team. Crit Care Med. 2006; 34(9 Suppl):S232-8.

Kurtz P, Fitts V, Sumer Z, Jalon H, Cooke J, Kvetan V, et al. How does care differ for neurological patients admitted to a neurocritical care unit versus a general ICU? Neurocrit Care. 2011; 15(3):477-80.

Chan C-L, Ting H-W, Huang H-T. The Definition of a Prolonged Intensive Care Unit Stay for Spontaneous Intracerebral Hemorrhage Patients: An Application with National Health Insurance Research Database. BioMed Research International. 2014; 2014:9.

Ingeman A, Andersen G, Hundborg HH, Svendsen ML, Johnsen SP. In-hospital medical complications, length of stay, and mortality among stroke unit patients. Stroke. 2011; 42(11):3214-8.

Hunter A, Johnson L, Coustasse A. Reduction of intensive care unit length of stay: the case of early mobilization. Health Care Manag (Frederick). 2014; 33(2):128-35.

Malkoc M, Karadibak D, Yildirim Y. The effect of physiotherapy on ventilatory dependency and the length of stay in an intensive care unit. Int J Rehabil Res. 2009; 32(1):85-8.

Naidech A, Bendok B, Tamul P, Bassin S, Watts C, Batjer HH, et al. Medical Complications Drive Length of Stay After Brain Hemorrhage: A Cohort Study. Neurocrit Care. 2009; 10(1):11-9.

How to Cite
Hasane Tamar S, Hoseini Hooshiar S, Karamimagham S, Poursadeghfard M. Epidemiology and Descriptive Analysis of Neuro-Critical Care Unit; Shiraz, South of Iran. AACC. 2(3):210-5.
Research Article(s)