Effect of Intravenous Meperidine in Controlling Post Dural Puncture Headache

  • Mohammad Reza Kamranmanesh Anesthesiology Research center, Labbafinejad Hospital, Shahid Beheshti University of Medical Sciences, School of Medicine, Tehran, Iran
  • Homayoun Aghamohammadi Anesthesiology Research center, Labbafinejad Hospital, Shahid Beheshti University of Medical Sciences, School of Medicine, Tehran, Iran
  • Alireza Jafari Anesthesiology Research center, Labbafinejad Hospital, Shahid Beheshti University of Medical Sciences, School of Medicine, Tehran, Iran
  • Yassaman Amini Anesthesiology Research center, Labbafinejad Hospital, Shahid Beheshti University of Medical Sciences, School of Medicine, Tehran, Iran
  • Babak Gharaei Anesthesiology Research center, Labbafinejad Hospital, Shahid Beheshti University of Medical Sciences, School of Medicine, Tehran, Iran
Keywords: meperidine, acetaminophen, post-dural puncture headache

Abstract

Background: Spinal anesthesia is usually applied for urologic surgeries. Postdural puncture headache (PDPH) is among common complications which has not been reduced during last years despite all advances in the field of medicine. Therapeutic effects of conventional therapy (paracetamol and novaphen) are being compared to intravenous meperidine in patients suffering from PDPH.Methods: One hundred patients, with PDPH following spinal anesthesia for transurethral lithotripsy were enrolled and randomly allocated to receive conventional (group C) or intravenous meperidine (group P) (20 mg every 5min up to 120mg or when the pain was decreased to less than 3/10).Results: Time interval to reach acceptable headache was 3 hours in group P compared to 8 hours in group C. Group P patients received statistically significantly less amount of paracetamol and novaphen, and experienced fewer episodes of severe headaches in 48 hours after the start of treatment, compared to group C.Conclusion: Short term intravenous meperidine compared to conventional therapy resulted in more rapid and effective outcomes.

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Published
2016-06-13
How to Cite
1.
Kamranmanesh MR, Aghamohammadi H, Jafari A, Amini Y, Gharaei B. Effect of Intravenous Meperidine in Controlling Post Dural Puncture Headache. AACC. 2(2):189-92.
Section
Research Article(s)