Risk Factors Affecting Deep Vein Thrombosis in Pregnant Women
Abstract
Background: One of the groups at risk for Deep Vein Thrombosis (DVT) is pregnant women. Considering the importance of pregnancy complications, the aim of this study was to determine the risk factors affecting DVT in the ICU.
Methods: In this study, pregnant women admitted to the ICU were included in the study, and instruments used in this study included a registry checklist that included questions. In this study, the clinical records of people with DVT were placed in 2 groups. The sample size included 28 patients with a diagnosis of DVT (case group) and 33 patients without a diagnosis of DVT (control group). Then, the data were analysed with SPSS 16.
Results: Results showed, in the 28 patients studied for whom the diagnosis of DVT was confirmed, the M(SD) of age status was 37.64 (2.57). There was also a significant association between DVT status with a history of thrombocytopenia, chronic diseases, diabetes, and high blood pressure (BP). (P<0.05).
Conclusion: In DVT, variables such as chronic diseases, diabetes, high blood pressure, and thrombocytopenia were effective. For this reason, it is essential to pay due attention to the factors affecting the development of DVT in clinical care for these patients.
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[22] Ebrahimisaraj G, Sarafi M, Ebrahimian M, Esmaeilizadeh AH, Ladan AH, Khoshkhabar M, et al. Short-term Outcomes of Pancreatectomy in Congenital Hyperinsulinism: A Retrospective Multi-center Study. Iran J Neonatol. 2023;14(2).
[23] Mohammadi HR, Erfani A, Sadeghi S, Komlakh K, Otaghi M, Vasig A. Investigating Factors Affecting Mortality Due to Spinal Cord Trauma in Patients Admitted to the Intensive Care Unit. Bull Emerg Trauma. 2024;12(3):136-41.
[24] Erfani A, Aghamiri SH, Karimi R. Investigating the Role of Hyper Density Signal Length in the Middle Cerebral Artery on the Degree of Disability of Arterial Ischemic Stroke Patients. Arch Neurosci. 2024;11(4):e150888.
[25] Azami M, Nasirkandy MP, Mansouri A, Darvishi Z, Rahmati S, Abangah G, et al. Global prevalence of helicobacter pylori infection in pregnant women: a systematic review and meta-analysis study. Int J Womens Health Reprod Sci. 2017;5(1):30-6.
[26] Anvari HM, Zeinalzadeh M, Ilkhchi NS, Alvandfar D. The factors affecting deep vein thrombosis following laparoscopic hysterectomy and the factors affecting it. The Iranian Journal of Obstetrics, Gynecology and Infertility. 2021; 24(11):17-23.
[27] Zhang C, Zhang X, Liu G. Deep vein thrombosis in early pregnancy: A retrospective study. Gynecol Obstet Clin Med. 2023;3(1):44-50.
[28] Mugeni R, Nkusi E, Rutaganda E, Musafiri S, Masaisa F, Lewis KL, et al. Proximal deep vein thrombosis among hospitalised medical and obstetric patients in Rwandan university teaching hospitals: prevalence and associated risk factors: a cross-sectional study. BMJ open. 2019; 9(11):e032604.
[29] Mahjobipoor H, Rahimi-Varposhti M, Shetabi H, Heidari S. Predictive factors of deep vein thrombosis in patients admitted to intensive care unit. Tehran Univ Med J. 2021;78(12):828-34.
[30] Miri M, Goharani R, Sistanizad M. Deep Vein Thrombosis among Intensive Care Unit Patients; an Epidemiologic Study. Emerg (Tehran). 2017;5(1):e13.
[31] Javadi Moghaddam M, Bakhshi Ali Abad H. Seasonal Changes in the Occurrence of Deep Vein Thrombosis (DVT) in Patients Referred to Aliebn-e-Abitaleb Hospital of Rafsanjan City in 2017: A Short Report. J Rafsanjan Univ Med Sci. 2020;18(11):1183-90.
[32] R Mousa B, E Mahdy N, Mahmoud SF, G Mohamed M. Risk factors for deep venous thrombosis among patients admitted to Vascular Unit. Egyptian Journal of Health Care. 2022;13(2):270-86.
[33] Takeda T, Koreki A, Kokubun S, Saito Y, Ishikawa A, Isose S, et al. Deep vein thrombosis and its risk factors in neurodegenerative diseases: A markedly higher incidence in Parkinson's disease. J Neurol Sci. 2024; 457:122896.
[2] Di Minno MN, Ambrosino P, Ambrosini F, Tremoli E, Di Minno G, Dentali F. Prevalence of deep vein thrombosis and pulmonary embolism in patients with superficial vein thrombosis: a systematic review and meta-analysis. J Thromb Haemost. 2016;14(5):964-72.
[3] Nicholson M, Chan N, Bhagirath V, Ginsberg J. Prevention of venous thromboembolism in 2020 and beyond. J Clin Med. 2020;9(8):2467.
[4] Geersing G, Zuithoff N, Kearon C, Anderson D, Ten Cate-Hoek A, Elf J, et al. Exclusion of deep vein thrombosis using the Wells rule in clinically important subgroups: individual patient data meta-analysis. Bmj. 2014;348.
[5] Naseri A, Dehghani A, Moharrami MR. Prevalence of deep vein thrombosis following knee replacement surgery in patients with a history of chemotherapy. Iran J Orthop Surg. 2021;
[6] Gram AS, Bladbjerg EM, Skov J, Ploug T, Sjödin A, Rosenkilde M, et al. Three months of strictly controlled daily endurance exercise reduces thrombin generation and fibrinolytic risk markers in younger moderately overweight men. Eur J Appl Physiol. 2015;115(6):1331-8.
[7] Niimi K, Nishida K, Lee C, Ikeda S, Kawai Y, Sugimoto M, et al. Optimal D-Dimer cutoff values for diagnosing deep vein thrombosis in patients with comorbid malignancies. Ann Vasc Surg. 2024; 98:293-300.
[8] Kitamura F, Shiraishi Y, Sakata K, Takata N, Harada K, Yoshinaka I, et al. Screening for Deep Vein Thrombosis Using D-dimer Levels Based on Surgical Patients’ Characteristics. Cureus. 2024;16(12):e75565.
[9] Kujovich JL. Hormones and pregnancy: thromboembolic risks for women. Br J Haematol. 2004;126(4):443-54.
[10] James AH, Jamison MG, Brancazio LR, Myers ER. Venous thromboembolism during pregnancy and the postpartum period: incidence, risk factors, and mortality. Am J Obstet Gynecol. 2006;194(5):1311-5.
[11] James AH, Tapson VF, Goldhaber SZ. Thrombosis during pregnancy and the postpartum period. Am J Obstet Gynecol. 2005;193(1):216-9.
[12] Devis P, Knuttinen MG. Deep venous thrombosis in pregnancy: incidence, pathogenesis and endovascular management. Cardiovasc Diagn Ther. 2017;7(Suppl 3):S309-s19.
[13] Putrie SW, Wicaksono B, Hadi THS. Unveiling a rare challenge: Giant cervical polyp in pregnancy: A case report and management insights. J Med Pharm Chem Res. 2025;7(9):1970-8.
[14] Suherman RWP, Akbar MIA. Maternal and perinatal outcomes in obese pregnant women. J Med Pharm Chem Res. 2025;7(7):1336-48
[15] Mezaal HD, Al-Fartosi KG, El Arbi M. Effect of sleep disturbance on the hormone melatonin and its relationship to some biochemical analyzes among some pregnant women in Thi-Qar governorate. J Med Pharm Chem Res. 2025;7(7):1411-9.
[16] Nabilah H, Akbar MIA, Joewono HT. The differences of risk factors and outcomes of pregnancy with obesity who had failed and successful induction of labor in 2023. J Med Pharm Chem Res. 2025;7(7):1503-12.
[17] Mallah F, Ilkhchi NS, Alvandfar D. The risk factors of deep vein thrombosis in pregnancy intensive care unit, Alzahra Hospital in Tabriz, 2019. The Iranian Journal of Obstetrics, Gynecology and Infertility, 2021; 24(11): 10-16.
[18] Kafeza M, Shalhoub J, Salooja N, Bingham L, Spagou K, Davies AH. A systematic review of clinical prediction scores for deep vein thrombosis. Phlebology. 2017;32(8):516-31.
[19] Hatefi M, Parvizi R, Borji M, Tarjoman A. Effect of self-management program on pain and disability index in elderly men with osteoarthritis. Anesth Pain Med. 2019;9(4).
[20] Mohajerzadeh L, Ebrahimian M, Sarafi M, Ebrahimisaraj G, Tabatabaei SR, Noorbakhsh SM, et al. Effects of COVID-19 Pandemic on the Frequency of Complicated Appendicitis in Pediatric Populations. Arch Pediatr Infect Dis. 2023;11(1).
[21] Esmaeilizadeh AH, Ebrahimisaraj G, Sarafi M, Rouzrokh M, Mohajerzadeh L, Ghoroubi J, et al. The outcome and complications of modern staged repair surgery in newborns with classic bladder exstrophy in different genders: A retrospective study. Birth Defects Research. 2023;115(16):1469-74.
[22] Ebrahimisaraj G, Sarafi M, Ebrahimian M, Esmaeilizadeh AH, Ladan AH, Khoshkhabar M, et al. Short-term Outcomes of Pancreatectomy in Congenital Hyperinsulinism: A Retrospective Multi-center Study. Iran J Neonatol. 2023;14(2).
[23] Mohammadi HR, Erfani A, Sadeghi S, Komlakh K, Otaghi M, Vasig A. Investigating Factors Affecting Mortality Due to Spinal Cord Trauma in Patients Admitted to the Intensive Care Unit. Bull Emerg Trauma. 2024;12(3):136-41.
[24] Erfani A, Aghamiri SH, Karimi R. Investigating the Role of Hyper Density Signal Length in the Middle Cerebral Artery on the Degree of Disability of Arterial Ischemic Stroke Patients. Arch Neurosci. 2024;11(4):e150888.
[25] Azami M, Nasirkandy MP, Mansouri A, Darvishi Z, Rahmati S, Abangah G, et al. Global prevalence of helicobacter pylori infection in pregnant women: a systematic review and meta-analysis study. Int J Womens Health Reprod Sci. 2017;5(1):30-6.
[26] Anvari HM, Zeinalzadeh M, Ilkhchi NS, Alvandfar D. The factors affecting deep vein thrombosis following laparoscopic hysterectomy and the factors affecting it. The Iranian Journal of Obstetrics, Gynecology and Infertility. 2021; 24(11):17-23.
[27] Zhang C, Zhang X, Liu G. Deep vein thrombosis in early pregnancy: A retrospective study. Gynecol Obstet Clin Med. 2023;3(1):44-50.
[28] Mugeni R, Nkusi E, Rutaganda E, Musafiri S, Masaisa F, Lewis KL, et al. Proximal deep vein thrombosis among hospitalised medical and obstetric patients in Rwandan university teaching hospitals: prevalence and associated risk factors: a cross-sectional study. BMJ open. 2019; 9(11):e032604.
[29] Mahjobipoor H, Rahimi-Varposhti M, Shetabi H, Heidari S. Predictive factors of deep vein thrombosis in patients admitted to intensive care unit. Tehran Univ Med J. 2021;78(12):828-34.
[30] Miri M, Goharani R, Sistanizad M. Deep Vein Thrombosis among Intensive Care Unit Patients; an Epidemiologic Study. Emerg (Tehran). 2017;5(1):e13.
[31] Javadi Moghaddam M, Bakhshi Ali Abad H. Seasonal Changes in the Occurrence of Deep Vein Thrombosis (DVT) in Patients Referred to Aliebn-e-Abitaleb Hospital of Rafsanjan City in 2017: A Short Report. J Rafsanjan Univ Med Sci. 2020;18(11):1183-90.
[32] R Mousa B, E Mahdy N, Mahmoud SF, G Mohamed M. Risk factors for deep venous thrombosis among patients admitted to Vascular Unit. Egyptian Journal of Health Care. 2022;13(2):270-86.
[33] Takeda T, Koreki A, Kokubun S, Saito Y, Ishikawa A, Isose S, et al. Deep vein thrombosis and its risk factors in neurodegenerative diseases: A markedly higher incidence in Parkinson's disease. J Neurol Sci. 2024; 457:122896.
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How to Cite
1.
Araiana S, Karimian M, Azimi B. Risk Factors Affecting Deep Vein Thrombosis in Pregnant Women. Arch Anesth & Crit Care. 2025;.
