Research Article

Evaluation of the Severity of Pain Caused by Management of Epistaxis in the Tertiary Center Emergency Department

Abstract

Background: Epistaxis can result from surgery, trauma, hypertension, hereditary hemorrhagic telangiectasia, or unknown reasons and can be treated in various ways. This study examined the pain severity related to epistaxis management in the emergency department of a tertiary otolaryngology facility.
Methods: This study was a descriptive and analytical cross-sectional analysis involving 129 patients. These patients were chosen from those referred to the emergency otolaryngology department for treatment of epistaxis. The treatment method was selected based on the severity of the epistaxis and whether a bleeding vessel was visible. Patients were categorized into nose pinching, anterior nasal packing, and bipolar electrocautery groups. For reducing pain from electrocautery and nasal packing, a mesh instilled with lidocaine and epinephrine is used before procedures. We assessed pain levels using a visual analog scale ranging from 0 to 10. We also studied the impact of xylocaine-prilocaine cream on reducing discomfort from anterior nasal packing in 42 patients who came to the emergency department with nosebleeds.
Results: The mean age of patients was 53.67 ± 19.96 years; 76 (57.6%) were male. Anterior nasal packing was the most common procedure for controlling epistaxis, with a mean pain severity of 6.61 (± 2.3). The pain score in the nostril-pinching group was significantly lower than in the other groups (P<0.001). In the second part of the study, the mean pain score in the xylocaine-prilocaine cream group was 4.52 ± 2.3, significantly lower than in the group without the cream (P<0.001).
Conclusion: According to the results, nasal packing was the most prevalent procedure for controlling epistaxis, which causes severe pain for patients. Application of xylocaine-prilocaine cream can reduce the severity of pain in comparison with lidocaine solution alone.

Viehweg TL, Roberson JB, Hudson JW. Epistaxis: diagnosis and treatment. J Oral Maxillofac Surg 2006;64:511–8.
[2] Doyle DE. Anterior epistaxis: a new nasal tampon for fast, effective control. Laryngoscope 1986;96:279–81.
[3] Jindal G, Gemmete J, Gandhi D. Interventional neuroradiology applications in otolaryngology, head and neck surgery. Otolaryngol Clin North Am 2012;45:1423–49.
[4] Tunkel DE, Anne S, Payne SC, Ishman SL, Rosenfeld RM, Abramson PJ, et al. Clinical Practice Guideline: Nosebleed (Epistaxis). Otolaryngol Head Neck Surg 2020;162:S1–38.
[5] Qureishi A, Burton MJ. Interventions for recurrent idiopathic epistaxis (nosebleeds) in children. Cochrane Database Syst Rev 2012;2012:CD004461.
[6] Bertrand B, Eloy P, Rombaux P, Lamarque C, Watelet JB, Collet S. Guidelines to the management of epistaxis. B-ENT 2005;Suppl 1:27–41; quiz 42–3.
[7] Kar M, Cetinkaya EA, Konşuk-Ünlü H. Comparison of the Ankaferd Blood Stopper Tampon and the Merocel Nasal Tampon after Septoplasty Surgery. Aesthetic Plast Surg 2023;47:294–300.
[8] Teymoortash A, Sesterhenn A, Kress R, Sapundzhiev N, Werner JA. Efficacy of ice packs in the management of epistaxis. Clin Otolaryngol Allied Sci 2003;28:545–7.
[9] Glynn F, Amin M, Sheahan P, Mc Shane D. Prospective double blind randomized clinical trial comparing 75% versus 95% silver nitrate cauterization in the management of idiopathic childhood epistaxis. Int J Pediatr Otorhinolaryngol 2011;75:81–4.
[10] El Sayed Ahmad Y, Kajal S, Halawi A. Managing Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT): A Comprehensive Narrative Review of Therapeutic Horizons. J Laryngol Otol 2024:1–25.
[11] Bansal BB, Kambala S, Nesiama J-A. Acute epistaxis: a comprehensive overview in the acute care setting. Pediatr Emerg Med Pract 2024;21:1–16.
[12] Seikaly H. Epistaxis. N Engl J Med 2021;384:944–51.
[13] Singer AJ, Blanda M, Cronin K, LoGiudice-Khwaja M, Gulla J, Bradshaw J, et al. Comparison of nasal tampons for the treatment of epistaxis in the emergency department: a randomized controlled trial. Ann Emerg Med 2005;45:134–9.
[14] Kumar M, Chawla R, Goyal M. Topical anesthesia. J Anaesthesiol Clin Pharmacol 2015;31:450–6.
[15] Daneshkazemi A, Abrisham SM, Daneshkazemi P, Davoudi A. The efficacy of eutectic mixture of local anesthetics as a topical anesthetic agent used for dental procedures: A brief review. Anesth Essays Res 2016;10:383–7.
[16] Randell T, Yli-Hankala A, Valli H, Lindgren L. Topical anaesthesia of the nasal mucosa for fibreoptic airway endoscopy. Br J Anaesth 1992;68:164–7.
[17] Özkiriş M, Aydin R, Gencer ZK, Saydam L. Comparison of topical anesthetic effects of lidocaine, prilocaine, ropivacaine, and bupivacaine in transnasal fiberoptic nasopharyngolaryngoscopy. Am J Rhinol Allergy 2014;28:e141–3.
[18] Haytoğlu S, Kuran G, Muluk NB, Arıkan OK. Different anesthetic agents-soaked sinus packings on pain management after functional endoscopic sinus surgery: which is the most effective? Eur Arch Otorhinolaryngol 2016;273:1769–77.
[19] Pieretti S, Di Giannuario A, Di Giovannandrea R, Marzoli F, Piccaro G, Minosi P, et al. Gender differences in pain and its relief. Ann Ist Super Sanita 2016;52:184–9.
Files
IssueArticle in Press QRcode
SectionResearch Article(s)
Keywords
Pain Epistaxis nasal packing Electrocautery Xylocaine-prilocaine cream

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
1.
Erfanian R, Abdullah H, Niknam M, Mokhtari Z, Abdollahi H, Keyfari Alamdari M. Evaluation of the Severity of Pain Caused by Management of Epistaxis in the Tertiary Center Emergency Department. Arch Anesth & Crit Care. 2025;.