Case Report

Accidental Intrathecal Injection of Atracurium During Spinal Anesthesia: A Case Report

Abstract

This case report outlines a rare occurrence of accidental intrathecal injection of atracurium during spinal anesthesia for knee arthroscopy in a 22-year-old male patient. The solution intended to be bupivacaine mixed with fentanyl raised concerns after the ampule was discarded before verification. Fortunately, the patient showed no signs of paralysis or analgesia post-injection. The anesthesia team promptly administered high-dose methylprednisolone to reduce potential neurotoxic effects and monitored the patient closely in the Post-Anesthesia Care Unit. After six hours of stability and no neurological deficits, follow-up evaluations confirmed no lasting damage, allowing for safe discharge after 24 hours. This incident underscores the critical need for rigorous drug verification and safety protocols in anesthesia to prevent medication errors.

[1] Kuvaki B, Özbilgin Ş, Küçük AB. Inadvertent intrathecal injection of Atracurium: a case report. Austin J Anesth Anal. 2017; 5:13.
[2] Zirak N, Soltani G, Ghomian N, Hasanpour MR, Mashayekhi Z. Inadvertent intrathecal injection of atracurium. Saudi journal of anaesthesia. 2011; 5(2):223-5.
[3] Lee SH, Choi TS, Han OS, Jung HS, Jang HS, Lee JS. Inadvertent Epidural Administration of Atracurium and Lidocaine Mixture: A case report. Korean J Anesthesiol. 2004; 47(4):600-2.
[4] Salihoglu Z, Demiroluk S, Kose Y. Accidental subarachnoid injection of atracurium: a case report. J Anesth. 2002;16(1):72-4.
[5] Singh E, Singh S, Singh S. Inadvertent Therapeutic Error Involving Spinal Anesthesia during Cesarean Section: A Case Report. J South Asian Fed Obst Gynaecol. 2022; 14(3):323-4.
[6] Ahmad M, Ackerman WE, Munir MA, McCourt CJ, Roberts W, Saberski LR. A simple technique to reduce preservative related neurotoxicity in epidural corticosteroid injections. Anesth Analg. 1999; 88(2S):269S.
Files
IssueArticle in Press QRcode
SectionCase Report(s)
Keywords
Atracurium Intrathecal injection Spinal anesthesia Human error Neuromuscular blockade Patient safety

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
1.
Ansar P, Tadjeddin N, Ariannia H, Behnaz F, Shojaei S. Accidental Intrathecal Injection of Atracurium During Spinal Anesthesia: A Case Report. Arch Anesth & Crit Care. 2025;.