Muscle Relaxants in Anesthesia Practice: A Narrative Review

  • Zahid Hussain Khan Professor of Anesthesiology and Critical Care, Deputy for Research, Department of Anesthesiology and Critical Care, Imam Khomeini Medical Complex, Tehran University of Medical Sciences, Tehran
  • Asghar Hajipour Department of Anesthesiology and Critical Care, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
  • Jayran Zebardast Department of Anesthesiology and Critical Care, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
  • Sami Raheem Alomairi Department of Anesthesiology and Critical Care, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Muscle relaxant, anesthesia practice


Background: The objective of this study is to review the literature about the muscle relaxants in anesthetic practice.

Methods: In this review, our search includes, the studies performed and applied between 2000 and 2016. Therefore, for review of muscle relaxants in anesthesia practice in major surgeries, we referred to Google scholar, UpToDate, science direct, Ovid MEDLINE, Springer, free journals and the references of reviewed articles in the English language.

Results: Neuromuscular blocking agents are a chore and essential part of balanced anesthesia. These are used to facilitate endotracheal intubation and provide skeletal muscle relaxation during surgery. The main disadvantage, i.e. residual paralysis, can be treated or prevented by reversing of such a block.

Conclusion: The muscle relaxant plays an important role in adequate muscle relaxation, which allows efficient and safe surgery, requiring automated ventilatory control.


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How to Cite
Khan Z, Hajipour A, Zebardast J, Alomairi S. Muscle Relaxants in Anesthesia Practice: A Narrative Review. Arch Anesth & Crit Care. 4(4):547-52.
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