Diagnostic Value of Troponin I and T to Predict Mortality in Patients Undergoing Hemodialysis

  • Seyed Taghi Hashemi Anesthesiology and Critical Care Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
  • Babak Alikiaii Mail Anesthesiology and Critical Care Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
  • Samira Ghasemi Medical School, Isfahan University of Medical Sciences, Isfahan, Iran.
Keywords:
Hemodialysis, Troponin T, Troponin I, Mortality.

Abstract

Background: There is no known biomarker to predict the mortality risk in patients undergoing dialysis in the intensive care unit (ICU). Therefore, the current study aimed to determine the diagnostic value of troponin I and T in this respect.
Methods: This prospective study included 70 patients, admitted to the intensive care unit, during 2016-2017, who need hemodialysis.
In these participants, the serum levels of troponin T and I were measured and the result of treatment was recorded in the patient’s profile whether it was improvement or death.
Finally, we analyzed the diagnostic value of troponin T and I was predict the mortality in these patients in SPSS software version 20 through the Rock analysis.
Results: The mean of troponin I and T levels in alive patients were 0.47±0.11 ng/ml and 0.67±0.15 ng/ml, respectively and in dead were 0.49±0.23 ng/ml and 1.06 ± 0.36 ng/ml, respectively. There was no significant difference between alive and dead patients in the mean of both troponins levels (P value> 0.05). On the other hand, Rock analysis also demonstrated that statistically these two biomarkers did not have any significant diagnostic value to predict mortality (P value> 0.05).
Conclusion: According to the results, it is conceivable that troponin I and T are not proper biomarkers to predict the mortality in patients undergoing dialysis in ICU and these biomarkers do not have a proper sensitivity and specificity for this purpose.

Author Biographies

Seyed Taghi Hashemi, Anesthesiology and Critical Care Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

Anaesthesiology and critical care at Isfahan

Babak Alikiaii, Anesthesiology and Critical Care Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

Anaesthesiology and critical care

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Published
2018-04-29
How to Cite
1.
Hashemi ST, Alikiaii B, Ghasemi S. Diagnostic Value of Troponin I and T to Predict Mortality in Patients Undergoing Hemodialysis. Arch Anesth & Crit Care. 4(2):464-7.
Section
Research Article(s)