Effect of Low Dose Lignocaine Injection in the Treatment of Post Stroke Pain: A Case Report
Pain experienced after a stroke is one of the worst experience for a given patient. Post stroke pain can present in various forms of which central post stroke pain (CPSP) is a neuropathic pain involving the area affected during the stroke. Till date there were different classes of medication used to treat CPSP without any promising results. This indirectly indicates so many mechanisms were included in these patients resulting in pain.
We would like report a case of CPSP successfully treated in our institute with low dose lignocaine injection peripherally.
We would like to conclude that the afferent sensory input from the painful area plays a role in maintaining the spontaneous (and the evoked) pain in CPSP which are getting blocked by giving low dose lignocaine injection peripherally. Further studies will be required to establish this novel treatment.
 Klit H, Finnerup NB, Jensen TS. Central post-stroke pain: clinical characteristics, pathophysiology, and management. Lancet Neurol. 2009; 8(9):857–68.
 Nicholson BD. Evaluation and treatment of central pain syndromes. Neurology 2004; 62:S30–36.
 Haroutounian S, Nikolajsen L, Bendtsen TF, Finnerup NB, Kristensen AD, Hasselstrom JB, et al. Primary afferent input critical for maintaining spontaneous pain in peripheral neuropathy. Pain. 2014; 155(7):1272–9.
 Onouchi K, Koga H, Yokoyama K, Yoshiyama T. An open-label, long-term study examining the safety and tolerability of pregabalin in Japanese patients with central neuropathic pain. J Pain Res. 2014; 7:439–44.
 Willoch F, Tolle TR, Wester HJ, Munz F, Petzold A, Schwaiger M, et al. Central pain after pontine infarction is associated with changes in opioid receptor binding: a PET study with 11C-diprenorphine. AJNR Am J Neuroradiol. 1999; 20(4):686-90.
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.