Research Article

The Comparisons of Intra-Peritoneal Bupivacaine Instillation versus Trendelenburg Position and Valsalva Maneuver on the Laparoscopic Cholecystectomy-induced Abdominal and Shoulder Pain

Abstract

Background: Although  laparoscopic   cholecystectomy  is   associated  with less  post-operative  pain compared  to  open  cholecystectomy,  diffuse shoulder  and  abdominal  pain  is   one    of   the    main postoperative complications in  this technique. The  aim  of this study was  to  compare the abdominal and shoulder pain after laparoscopic cholecystectomy by  applying intra-abdominal  bupivacaine instillation versus the  trendelenburg position and valsalva maneuver.
Methods: A double blind randomized clinical trial was  conducted in the university hospital. 120  patients aged 25-55 years were scheduled for  elective laparoscopic cholecystectomy and without any  history of previous surgery, pregnancy or acute abdomen were enrolled. Patients were allocated into 4 groups (each30 cases)Group 1 received just intra-peritoneal normal saline (NS). Group 2 patients who were placed intrendelenburg  position  plus valsalva maneuver  and  received intra-peritoneal  NS.  For   group 3,  intra- peritoneal bupivacaine instillation was  done. Patients in group 4 received intra-peritoneal bupivacaine as well as  were placed in  trendelenburg position plus valsalva maneuver. Post-operative pain severity using visual analog scale, analgesic requirement and nausea and vomiting were recorded in all patients.
Results: Total mean pain score at 24 hours was  3.55±0.47 in group 1, 1.08 ±0.85 in group 2, 0.33  ±0.14  in group 3, and 0.20  ±0.59  in group 4 (P= 0.001). Mean total score of shoulder pain was  4.70  ±2.18  in group1, 1.23  ±0.11  in group 2, 1.18  ±0.11  in group 3, and 0.70  ±0.12  in group 4 (P= 0.001).
Conclusion: Combined  intra-peritoneal   bupivacaine  with trendelenburg  positioning  and   valsalva maneuver   was  superior   to either one alone in decreasing pain severity after laparoscopic cholecystectomy.

 

Castro PM, Akerman D, Munhoz CB, Sacramento Id, Mazzurana M, Alvarez GA. Laparoscopic cholecystectomy versus minilaparotomy in cholelithiasis: systematic review and meta-analysis. Arq Bras Cir Dig. 2014; 27(2):148-53.

Ortiz J, Chang LC, Tolpin DA, Minard CG, Scott BG, Rivers JM. Randomized, controlled trial comparing the effects of anesthesia with propofol, isoflurane, desflurane and sevoflurane on pain after laparoscopic cholecystectomy. Braz J Anesthesiol. 2014; 64(3):145-51.

Chundrigar T, Hedges AR, Morris R, Stamatakis JD. Intraperitoneal bupivacaine for effective pain relief after laparoscopic cholecystectomy. Ann R Coll Surg Engl. 1993; 75(6):437-9.

Gautam S, Agarwal A, Das PK, Agarwal A, Kumar S, Khuba S. Evaluation of the efficacy of methylprednisolone, etoricoxib and a combination of the two substances to attenuate postoperative pain and PONV in patients undergoing laparoscopic cholecystectomy: a prospective, randomized, placebo-controlled trial. Korean J Pain. 2014; 27(3):278-84.

Akkurt BC, Temiz M, Inanoglu K, Aslan A, Turhanoglu S, Asfuroglu Z, et al. Comparison of recovery characteristics, postoperative nausea and vomiting, and gastrointestinal motility with total intravenous anesthesia with propofol versus inhalation anesthesia with desflurane for laparoscopic cholecystectomy: A randomized controlled study. Curr Ther Res Clin Exp. 2009; 70(2):94-103.

Joris J, Thiry E, Paris P, Weerts J, Lamy M. Pain after laparoscopic cholecystectomy: characteristics and effect of intraperitoneal bupivacaine. Anesth Analg. 1995; 81(2):379-84.

Tobias JD. Pain management following laparoscopy: Can we do better? Saudi J Anaesth. 2013; 7:3-4.

Phelps P, Cakmakkaya OS, Apfel CC, Radke OC. A simple clinical maneuver to reduce laparoscopy-induced shoulder pain: a randomized controlled trial. Obstet Gynecol. 2008; 111(5):1155-60.

Papadima A, Lagoudianakis EE, Antonakis P, Filis K, Makri I, Markogiannakis H, et al. Repeated intraperitoneal instillation of levobupivacaine for the management of pain after laparoscopic cholecystectomy. Surgery. 2009; 146(3):475-82.

Louizos AA, Hadzilia SJ, Leandros E, Kouroukli IK, Georgiou LG, Bramis JP. Postoperative pain relief after laparoscopic cholecystectomy: a placebo-controlled double-blind randomized trial of preincisional infiltration and intraperitoneal instillation of levobupivacaine 0.25%. Surg Endosc. 2005; 19(11):1503-6.

Papagiannopoulou P, Argiriadou H, Georgiou M, Papaziogas B, Sfyra E, Kanakoudis F. Preincisional local infiltration of levobupivacaine vs ropivacaine for pain control after laparoscopic cholecystectomy. Surg Endosc. 2003; 17(12):1961-4.

Jackson SA, Laurence AS, Hill JC. Does post-laparoscopy pain relate to residual carbon dioxide? Anaesthesia. 1996; 51(5):485-7.

Thomson AJ, Abbott JA, Lenart M, Willison F, Vancaillie TG, Bennett MJ. Assessment of a method to expel intraperitoneal gas after gynecologic laparoscopy. J Minim Invasive Gynecol. 2005; 12(2): 125-9.

Raetzell M, Maier C, Schröder D, Wulf H. Intraperitoneal application of bupivacaine during laparoscopic cholecystectomy--risk or benefit? Anesth Analg. 1995; 81(5):967-72.

Smith T. Ethics in medical research. 1st ed. UK: Cambridge University Press; 1999. p. 12–49.

Tsai HW, Chen YJ, Ho CM, Hseu SS, Chao KC, Tsai SK, et al. Maneuvers to decrease laparoscopy-induced shoulder and upper abdominal pain: a randomized controlled study. Arch Surg. 2011; 146(12):1360-6.

Sharami SH, Sharami MB, Abdollahzadeh M, Keyvan A. Randomised clinical trial of the influence of pulmonary recruitment manoeuvre on reducing shoulder pain after laparoscopy. J Obstet Gynaecol. 2010; 30(5):505-10.

Tsimoyiannis EC, Siakas P, Tassis A, Lekkas ET, Tzourou H, Kambili M. Intraperitoneal normal saline infusion for postoperative pain after laparoscopic cholecystectomy. World J Surg. 1998; 22(8):824-8.

Golubović S, Golubović V, Cindrić-Stancin M, Tokmadzić VS. Intraperitoneal analgesia for laparoscopic cholecystectomy: bupivacaine versus bupivacaine with tramadol. Coll Antropol. 2009; 33(1):299-302.

Mraović B, Jurisić T, Kogler-Majeric V, Sustic A. Intraperitoneal bupivacaine for analgesia after laparoscopic cholecystectomy. Acta Anaesthesiol Scand. 1997; 41(2): 193-6.

Jiranantarat V, Rushatamukayanunt W, Lert-akyamanee N, Sirijearanai R, Piromrat I, Suwannanonda P, et al. Analgesic effect of intraperitoneal instillation of bupivacaine for postoperative laparoscopic cholecystectomy. J Med Assoc Thai. 2002; 85 Suppl 3:S897-903.

Szem JW, Hydo L, Barie PS. A double-blinded evaluation of intraperitoneal bupivacaine vs saline for the reduction of postoperative pain and nausea after laparoscopic cholecystectomy. Surg Endosc. 1996; 10:44-8.

Files
IssueVol 1 No 3 (2015): Summer QRcode
SectionResearch Article(s)
Keywords
laparoscopic cholecystectomy pain trendelenburg position valsalva maneuver

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
1.
Farhanchi A, Rahmani M, Moharamzadeh L, Kalani P. The Comparisons of Intra-Peritoneal Bupivacaine Instillation versus Trendelenburg Position and Valsalva Maneuver on the Laparoscopic Cholecystectomy-induced Abdominal and Shoulder Pain. Arch Anesth & Crit Care. 2015;1(3):67-71.