A Comprehensive Review on Wound Dressings and Their Comparative Effectiveness on Healing of Contaminated Wounds and Ulcers
,
Abstract
A wound could happen at any accident or surgery. Generally, bleeding wounds, serious wounds and infectious wounds need to be taken care for recovery and in case of germ infection, wound recovery and management is a complicated process. The process including wound pre-cleaning, wound healing, infection prevention, germ treatment and dressings. The application of wound dressings play a very critical role in wound healing and infection prevention. When a wound is exposed to the pathogens and foreign substances but results in no signs of infection, it is then called as a contaminated wound. The colonized wounds are chronic, where in there are multiple pathogens present in the wound. This occurs frequently in patients who have diabetic foot and pressure ulcers. Hence, management of the diabetic involves great acceleration of foot ulceration. Ideally, dressing should alleviate symptoms, provide wound protection and healing. No single dressing fulfills all the requirements of patient with an infected foot ulcer and other contaminated wounds. However, every category of dressings has specific characteristics that aid selection. There are various types of wound dressings such as, foam and alginate dressings are highly absorbent and effective for heavily exuding wounds. The hydrogel wound dressing treatment facilitate autolysis and may be beneficial in managing ulcers containing necrotic tissue. Dressings containing iodine and silver encourage in managing wound infection and it is more efficient. For infected wounds occlusive dressings should be avoided. For the wound inspection all dressings require frequent change. Deeply exudating ulcers need regular change to reduce maceration of surrounding skin. Dressing choice should be guided by the characteristics of the ulcer, the requirements of the patient, and the involved in wound care cost. These dressings display their own advantages and disadvantages in the wound treatments. As a physician has to deal with many patients with different types of wound like acute, chronic, burn and foot ulcers conditions every day. It is thereby very important and helpful to have a good knowledge about the right type of dressing for particular wound and also the right time for wound dressings for patient’s prognosis. In this review, we will discuss the different wound dressings and its comparative effectiveness on contaminated wound and ulcer.
[2] Fife CE, Carter MJ. Wound Care Outcomes and Associated Cost Among Patients Treated in US Outpatient Wound Centers: Data From the US Wound Registry. Wounds. 2012; 24(1):10-7.
[3] Leask A. Potential therapeutic targets for cardiac fibrosis: TGFbeta, angiotensin, endothelin, CCN2,and PDGF, partners in fibroblast activation. Circ Res.2010; 106(11):1675-80.
[4] Al-Gharibi KA, Sharstha S, Al-Faras MA. Cost-Effectiveness of Wound Care: A concept analysis.Sultan Qaboos Univ Med J. 2018; 18(4):e433-e439.
[5] Sood A, Granick MS, Tomaselli NL. Wound Dressings and Comparative Effectiveness Data. Adv Wound Care (New Rochelle). 2014; 3(8):511-529.
[6] Velnar T, Bailey T, Smrkolj V. The wound healing process: an overview of the cellular and molecular mechanisms. J Int Med Res. 2009; 37(5):1528-42.
[7] Han G, Ceilley R. Chronic wound healing: A review of current management and treatments. Adv Ther.2017; 34(3):599-610.
[8] Malone M. The microbiome of Diabetic foot ulcers and the role of Biofilms. Adv Immunol. 2018;
[9] Leung A, Crombleholme TM, Keswani SG. Fetal wound healing: implications for minimal scar formation. Curr Opin Pediatr. 2012; 24(3):371-8.
[10] Larson BJ, Longaker MT, Lorenz HP. Scarless fetal wound healing: a basic science review. Plast Reconstr Surg. 2010; 126(4):1172-1180.
[11] Daunton C, Kothari S, Smith L, Steele D. A history of materials and practices for wound management. Wound Pract Res. 2012; 20: 174- 86.
[12] Shah JB. The history of wound care. J Am Col Certif Wound Spec. 2011; 3(3):65-6.
[13] Dhivya S, Padma VV, Santhini E. Wound dressings - a review. Biomedicine (Taipei). 2015; 5(4):22.
[14] Öztürk E, Ağalar C, Keçeci K, Denkbas̨ EB. Preparation and characterization of ciprofloxacinloaded alginate/chitosan sponge as a wound dressing material. Journal of applied polymer science. 2006;101(3):1602-9.
[15] Maleki H, Gharehaghaji A, Dijkstra P. A novel honey-based nanofibrous scaffold for wound dressing application. J Appl Polym Sci. 2013, 127(5):4086-92.
[16] Boateng JS, Matthews KH, Stevens HE, Eccleston GM. Wound healing dressings and drug delivery systems: A review. J Pharm Sci. 2008; 97:2892– 2923.
[17] Domb A. Focal controlled drug delivery. New York[u.a.]: Springer; 2014; 585.
[18] Varaprasad K, Mohan YM, Vimala K, Mohana Raju K. Synthesis and characterization of hydrogel-silver nanoparticle-curcumin composites for wound dressing and antibacterial application. J Appl Polym Sci. 2011; 121, 784.
[19] Boateng JS, Matthews KH, Stevens HN, Eccleston GM. Wound healing dressings and drug delivery systems: a review. J Pharm Sci. 2008; 97(8):2892-923.
[20] Gumargalieva KZ, Zaikov GE. In Key Engineering Materials, Volume 2: Interdisciplinary Concepts and Research; Kajzar, F.; Pearce, E. M.; Turovskij, N. A.; Mukbaniani, O. V., Eds., CRC Press: Oakville, 2014.
[21] Simões D, Miguel SP, Ribeiro MP, Coutinho P, Mendonça AG, Correia IJ. Recent advances on antimicrobial wound dressing: A review. Eur J Pharm Biopharm. 2018; 127:130-141.
[22] Rezvani Ghomi E, Khalili S, Nouri Khorasani S, Esmaeely Neisiany R, Ramakrishna S. Wound dressings: Current advances and future directions. J Appl Polym Sci. 2019; 136 (27):47738.
[23] Radhika P, Arun Kumar K. Herbal Hydrogel for Wound Healing: A Review. Int J Pharma Res. Health Sci. 2017; 5(2):1616-22.
[24] Suganya, S, Senthil Ram T, Lakshmi B S, Giridev V R. Herbal drug incorporated antibacterial nanofibrous mat fabricated by electrospinning: An excellent matrix for wound dressings. J Appl Polym Sci. 2011 121(5):2893-9.
[25] Pourhojat F, Sohrabi, M, Shariati, S, Mahdavi, H, Asadpour L. Preparation of antibacterial electrospun Polylactic-co–glycolic acid nanofibers containing Hypericum Perforatum with bedsore healing property and evaluation of its drug release performance. Res Chem Intermed. 2017; 9(3):286-97.
[26] Akbar A R, Su S, Amjad B, Cai Y; Lin L. Effect of Bamboo Viscose on the Wicking and Moisture Management Properties of Gauze. IOP Conf Series Mater Sci Eng. 2017, 275, 012042.
[27] Dhivya S, Padma VV, Santhini E. Wound dressings - a review. Biomedicine (Taipei). 2015; 5(4):22.
[28] Moshakis V, Fordyce MJ, Griffiths J D, McKinna JA. Tegaderm versus gauze dressing in breast surgery. Br J Clin Pract. 1984; 38(4): 149-52.
[29] Ramos-e-Silva M, Ribeiro de Castro MC. New dressings, including tissue-engineered living skin. Clin Dermatol. 2002; 20(6):715-23.
[30] Maver T, Maver U, Pivec T, Kurečič M, Persin Z, Kleinschek KS. Bioactive Polysaccharide Materials for Modern Wound Healing. Springer; Berlin/Heidelberg, Germany: 2018. Advanced wound care. 1–8.
[31] Aruan NM., Sriyanti I, Edikresnha D, Suciati T, Munir M.M, Khairurrijal. Polyvinyl Alcohol/Soursop Leaves Extract Composite Nanofibers Synthesized Using Electrospinning Technique and their Potential as Antibacterial Wound Dressing. Procedia Eng. 2017; 170:31–35.
[32] Weller C, Weller C, Team V. 4—Interactive dressings and their role in moist wound management. In: Rajendran S., editor. Advanced Textiles for Wound Care. 2nd ed. Woodhead Publishing; Sawton, Cambridge, UK: 2019. pp. 105–134.
[33] Thomson T. Foam Composite. US Patent 7048966. 2006.
[34] Martin L, Wilson CG, Koosha F, Tetley L, Gray AI, Senel S, et al. The release of model macromolecules may be controlled by the hydrophobicity of palmitoyl glycol chitosan hydrogels. J Control Release. 2002; 80(1-3):87-100.
[35] Salehi H, Mehrasa M, Nasri-Nasrabadi B, Doostmohammadi M, Seyedebrahimi R, Davari N, et al. Effects of nanozeolite/starch thermoplastic hydrogel on wound healing. J Res Med Sci.2017; 22:110.
[36] Warriner R, Burrell R. Infection and the chronic wound: a focus on silver. Adv Skin Wound Care. 2005; 18 Suppl 1:2-12.
[37] Lu H, Yuan L, Yu X, Wu C, He D, Deng J. Recent advances of on-demand dissolution of hydrogel dressings. Burns Trauma. 2018; 6:35.
[38] Derwin R, Moore ZEH, Webster J. Hydrocolloid dressings for donor sites of split thickness skin grafts. Cochrane Database Syst. Rev. 2018;2018:CD012634.
[39] Hansson C. Interactive wound dressings. Drugs & aging. 1997 Oct;11(4):271-84.
[40] Pawar HV, Tetteh J, Debrah P, Boateng JS. Comparison of in vitro antibacterial activity of streptomycin-diclofenac loaded composite biomaterial dressings with commercial silver based antimicrobial wound dressings. Int. J. Biol. Macromol. 2019; 121:191–199.
[41] Warriner R, Burrell R. Infection and the chronic wound: a focus on silver. Adv Skin Wound Care. 2005; 18 Suppl 1:2-12.
[42] Burrell BE. A scientific perspective on the use of topical silver preparations. Ostomy Wound Manage.2003; (49):19.
[43] Tomaselli N: The role of topical silver preparations in wound healing. J Wound Ostomy Continuence Nurs. 2006; 33(4): 367-78.
[44] Leaper DJ. Silver dressings: their role in wound management. Int Wound J. 2006; 3(4):282–94.
[45] Dissemond J, Gerber V, Kramer A, Riepe G, Strohal R, Vasel-Biergans A, Eberlein T. A practice-oriented recommendation for treatment of critically colonised and locally infected wounds using polihexanide. J Tissue Viability. 2010; 19(3):106-15.
[46] Eberlein T, Haemmerle G, Signer M, Gruber Moesenbacher U, Traber J, Mittlboeck M, et al. Comparison of PHMB-containing dressing and silver dressings in patients with critically colonised or locally infected wounds. J Wound Care. 2012; 21(1): 12, 14-6.
[47] Molan P, Rhodes T. Honey: A Biologic Wound Dressing. Wounds. 2015; 27(6):141-51.
[48] Vermeulen H, Westerbos SJ, Ubbink DT. Benefit and harm of iodine in wound care: a systematic review. J Hosp Infect. 2010; 76(3):191-9.
[49] Wang PH, Huang BS, Horng HC, Yeh CC, Chen YJ. Wound healing. J Chin Med Assoc. 2018; 81(2):94-101.
| Files | ||
| Issue | Vol 8 No 2 (2022): Spring |
|
| Section | Review Article(s) | |
| DOI | https://doi.org/10.18502/aacc.v8i2.9158 | |
| Keywords | ||
| Wound healing bacterial contaminated wound dressing therapies cost effectiveness | ||
| Rights and permissions | |
|
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
