Analysis of Epidemiological and Clinical Factors of Patients Admitted to Covid ICU Setup in a Tertiary Care Center during Second Wave in India: A Retrospective Observational Study

Abstract

Background: Covid-19 has been associated with more than 330 million cases and 5.5 million deaths since December 2019 with many countries witnessing two or three waves of covid -19 cases. In our study we retrospectively analysed data of patients admitted to Intensive Care Unit of a tertiary care hospital in India with moderate to severe disease for association of mortality with comorbidities, gender and age of patients.
Methods: Data of patients admitted to Intensive care unit of our hospital from march 2021 to august 2021 with moderate to severe covid infection was retrospectively collected, patients with incomplete data in records were excluded and data of total of 415 patients was analysed for association of comorbidities (Diabetes, CKD, CAD, Hypertension, Chronic respiratory illness), gender and age for any association with mortality by multivariate binary logistic analysis and chi square test.
Results: There was significant association of increased mortality with age more than 50 yrs having an odds ratio of 1.5 and age more than 70 yrs having odds ratio of 2.46(p= 0.027). There was also significant association between CKD and mortality with odds ratio of 3.117. (p =0.050).
No association between Diabetes, CAD, Hypertension, Chronic respiratory illness and gender was found in our study.
Conclusion: The novel coronavirus infection (COVID-19) has significantly increased mortality in patients of age more than 50 yrs, the risk increases further if age is more than 70 yrs. We also found increased mortality in patients with chronic kidney disease.