The Effect of Remifentanil– Propofol Compared with Fentanyl– Propofol on Urine Output in Patients Undergoing Lumbar Posterior Spinal Fusion
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Abstract
Background: Remifentanil is a narcotic drug used in anaesthesia for establishment of hemodynamic stability. The purpose of this study was to compare the effects of remifentanil and fentanyl on urine excretion.
Methods: In a randomized clinical trial, 60 patients, who were candidates for elective surgery for lumbar posterior spinal fusion, were divided randomly into two groups of 30 as remifentanil – propofol (R) and fentanyl- propofol (F). Maintenance of anaesthesia drugs in group R included 100 mcg/kg/min propofol and 0.5- 0.25 mcg/kg/min remifentanil. It included 100 mcg/kg/min propofol and 5- 0.5 mcg/kg/min fentanyl in group F. Vital signs and urine output were recorded every half an hour.
Results: The mean age of patients was 49.5± 12.7 years. Urine output in group R showed significantly greater reduction than in group F (p< 0.001). Increase of urine output was seen in both groups over the time.
Conclusion: Urine output in patients undergoing lumbar posterior spinal fusion who received remifentanil was less compared to the fentanyl group.
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| Issue | Vol 2 No 2 (2016): Spring |
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| Section | Research Article(s) | |
| Keywords | ||
| remifentanil propofol fentanyl urine output lumbar posterior spinal fusion | ||
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