Research Article

Comparison of Clonidine versus Esmolol in Controlled Hypotension in Patients Undergoing FESS Surgery

Abstract

Background: FESS has its share of complications which can be a challenge for both the surgeon as well the anesthetist and achieving a bloodless surgical field is essential So the principle of controlled hypotension can be used to combat this issue.
Methods: A hospital-based randomized comparative interventional study was conducted on 60 patients to compare Clonidine (2mcg/kg in 10 ml of saline over 10 minutes before induction followed by an infusion of 1mcg/kg/hr during maintenance) and Esmolol (1mg/kg in 10 ml of saline over 10 minutes before induction followed by an infusion of 1mg/kg/hr during maintenance) to assess and compare the hypotensive properties of both the drugs.
Results: After the induction of anesthesia, there was a significant difference in the mean heart rate, and mean arterial pressure between the two groups throughout the intraoperative period (p-value < 0.05). Both groups achieved a target mean arterial pressure (MAP) of 65-70 mmHg and improved surgical field quality.
Conclusion: This study concluded that clonidine and esmolol both provide hemodynamic stability and a better surgical field in functional endoscopic sinus surgery (FESS). Clonidine also helps in achieving postoperative sedation and analgesia.

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IssueVol 10 No 1 (2024): Winter QRcode
SectionResearch Article(s)
DOI https://doi.org/10.18502/aacc.v10i1.14765
Keywords
Controlled hypotension Clonidine Esmolol
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How to Cite
1.
Garg K, Nanda S, Bafna U, Mali C, Naaz S, Sabu N. Comparison of Clonidine versus Esmolol in Controlled Hypotension in Patients Undergoing FESS Surgery. Arch Anesth & Crit Care. 2023;10(1):3-8.