Cardiomyopathy with Pancytopenia in a Pregnancy: Case Reports
Abstract
Anemia, a common symptom in pregnancy, can lead to life-threatening cardiomyopathy.
A 30-years old gravida 2 para 1 woman was admitted at 34 weeks of gestational age with asymptomatic pancytopenia and vitamin B12 deficiency in the laboratory tests. She also had a diet-controlled gestational diabetes, megaloblastic changes in Bone marrow aspiration and cardiomyopathy shown by echocardiography. The patient recovered from pancytopenia and cardiomyopathy after one week treatment with vitamin B12 and folate.
In this case, cardiomyopathy worsened with anemia. By treating vitamin B12 deficiency, cardiomyopathy can be prevented or controlled during pregnancy. Careful consideration is needed when assessing anemia in pregnant women on vegetarian diet and at higher risk.
[2] Imran M, Helmy YA, Hafez MFA. Anemia with prgnancy. Sohag Medical Journal. 2019.
[3] Di Renzo GC, Spano F, Giardina I, Brillo E, Clerici G, Roura LC. Iron deficiency anemia in pregnancy. Women’s Health. 2015; 11(6):891-900.
[4] Idris N, Arsyad A. Vitamin B12 deficiency presenting as pancytopenia in pregnancy: a case report. Malays Fam Physician. 2012; 7(2-3):46-50.
[5] Hasbaoui BE, Mebrouk N, Saghir S, Yajouri AE, Abilkassem R, Agadr A. Vitamin B12 deficiency: case report and review of literature. Pan Afr Med J. 2021; 38:237.
[6] Liu Y, Geng T, Wan Z, Lu Q, Zhang X, Qiu Z, et al. Associations of serum folate and vitamin B12 levels with cardiovascular disease mortality among patients with type 2 diabetes. JAMA network open. 2022; 5(1):e2146124-e.
[7] Bhowmik B, Siddiquee T, Mdala I, Nesa LQ, Shelly SJ, Hassan Z, et al. Vitamin D3 and B12 supplementation in pregnancy. Diabetes Res Clin Pract. 2021; 174:108728.
[8] Patel P, Balanchivadze N. Hematologic Findings in Pregnancy: A Guide for the Internist. Cureus. 2021; 13(5).
[9] Małyszko J, Tomaszuk-Kazberuk A, Dobrzycki K, Bachórzewska-Gajewska H, Zorawski M, Koc-Zorawska E, et al. Vitamin D deficiency and anemia is highly prevalent and dependent on the etiology of heart failure: A pilot study. Cardiol J. 2021; 28(2):262-70.
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| Issue | Article in Press |
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| Section | Case Report(s) | |
| Keywords | ||
| Cardiomyopathy Pancytopenia Pregnancy Vitamin B12 deficiency | ||
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