Archives of Anesthesiology and Critical Care 2015. 1(4):130-133.

The Perioperative Effects of Statins in Non Cardiac Surgeries
Atieh Rezaeefar, Reza Shariat Moharari, Atabak Najafi, Mohammad Reza Khajavi


Background: Statins (3-Hydroxy-3-methylglutarylcoenzyme-A (HMG-CoA) reductase inhibitors) decrease cardiovascular mortality and morbidity. This article reviews the role of perioperative statins in non cardiac surgery.

Methods: A literature review was done on all English published articles till February 2015 about this subject using pubmed. Then the reference list of relevant articles was reviewed for additional resources.

Results: Current evidence shows that not only statins decrease perioperative morbidity and mortality in patients undergoing non cardiac surgery, but also they seem safe during perioperative period.

Conclusion: A properly designed randomized control trial should be performed to assess the perioperative benefits of statins in non cardiac surgery.


statins; non cardiac surgery; perioperative periods

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