Anesthesia Management in Achondroplasia: A Case Report
Achondroplasia is the result of a mutation in the gene encoding the type 3 receptor for a fibroblast growth factor. This abnormality results in malformation endochondral ossification. Achondroplasia is characterized by disproportionately short stature, lumbar lordosis, large head, midface hypoplasia, short hands, and normal cognitive development.
Our report is about a 28-year-old patient with achondroplasia who underwent surgery for correction of kyphosis due to spinal canal stenosis. In this present case we study management anesthesia.
 Horton WA, Hall JG, Hecht JT. Achondroplasia. Lancet. 2007; 370(9582):162-172.
 Baujat G, Legeai-Mallet L, Finidori G, Cormier-Daire V, Le Merrer M. Achondroplasia. Best Pract Res Clin Rheumatol. 2008; 22(1):3-18.
 Wright MJ, Irving MD. Clinical management of achondroplasia. Arch Dis Child. 2012; 97(2):129-34.
 Trotter TL, Hall JG. Health supervision for children with achondroplasia. Pediatrics. 2005; 116(3):771-83.
 Ireland PJ, Johnson S, Donaghey S, Johnston L, Ware RS, Zankl A, et al. Medical management of children with achondroplasia: evaluation of an Australasian cohort aged 0–5 years. J Paediatr Child Health. 2012; 48(5):443-9.
 Shirley ED, Ain MC. Achondroplasia: manifestations and treatment. J Am Acad Orthop Surg. 2009; 17(4):231-41.
 Hunter AG, Bankier A, Rogers JG, Sillence D, Scott CI. Medical complications of achondroplasia: a multicentre patient review. J Med Genet. 1998; 35(9):705-12.
 White KK, Bompadre V, Goldberg MJ, Bober MB, Campbell JW, Cho TJ, et al. Best practices in the evaluation and treatment of foramen magnum stenosis in achondroplasia during infancy. Am J Med Genet A. 2016; 170A(1):42-51.
 Wynn J, King TM, Gambello MJ, Waller DK, Hecht JT. Mortality in achondroplasia study: A 42-year follow-up. Am J Med Genet A. 2007; 143(21):2502-11.
 Cardenas P, Lyons LM. 86 Achondroplasia. Decision Making in Anesthesiology. 2019; 264.
 Dubiel L, Scott GA, Agaram R, McGrady E, Duncan A, Litchfield KN. Achondroplasia: anaesthetic challenges for caesarean section. Int J Obstet Anesth. 2014; 23 (3):274-8.
|Issue||Vol 7 No 2 (2021): Spring|
|Anesthesia Achondroplasia Autosomal dominant Airway management|
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