Takotsubo Cardiomyopathy as a Complication/Sequelae of Prolonged Refractory Seizure: A Case Report from Nepal
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Abstract
Takotsubo cardiomyopathy(TC) is a reversible, yet underdiagnosed cause of mortality and morbidity in the intensive care units. It occurs secondary to sudden catecholamine surge precipitated by any form of emotional or pathological stress. Association between central nervous system disorders and Takotsubo cardiomyopathy is being increasingly reported. Epilepsy is the second most common CNS disorder to trigger TC, SAH being the first. We report a case of TC in an elderly man with prolonged, recurrent seizure episodes refractory to the commonly used antiepileptic drugs (AEDs), who developed unexplained tachycardia, hypotension and elevated cardiac enzymes.
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[6] Prasad A, Lerman A, Rihal CS. Apical ballooning syndrome (Tako-Tsubo or stress cardiomyopathy): a mimic of acute myocardial infarction. Am Heart J. 2008;155(3):408-17.
[7] Bennett JR, McCarty D, Wilson CM, O'Neill F. Takotsubo cardiomyopathy: an uncommon cause of ST segment elevation in intensive care. Anaesthesia. 2007;62(3):279-81.
[8] Finsterer J, Wahbi K. CNS disease triggering Takotsubo stress cardiomyopathy. Int J Cardiol. 2014;177(2):322-9.
[9] Bybee KA, Kara T, Prasad A, Lerman A, Barsness GW, Wright RS, et al. Systematic review: transient left ventricular apical ballooning: a syndrome that mimics ST-segment elevation myocardial infarction. Ann Intern Med. 2004;141(11):858-65.
[2] Abdulla I, Kay S, Mussap C, Nelson GI, Rasmussen HH, Hansen PS, et al. Apical sparing in tako-tsubo cardiomyopathy. Intern Med J. 2006; 36(7):414-8.
[3] Wittstein IS, Thiemann DR, Lima JA, Baughman KL, Schulman SP, Gerstenblith G, et al. Neurohumoral features of myocardial stunning due to sudden emotional stress. N Engl J Med. 2005; 352(6):539-48.
[4] Stöllberger C, Wegner C, Finsterer J. Seizure-associated Takotsubo cardiomyopathy. Epilepsia. 2011;52(11):e160-7.
[5] Dawson DK. Acute stress-induced (takotsubo) cardiomyopathy. Heart. 2018;104(2):96-102.
[6] Prasad A, Lerman A, Rihal CS. Apical ballooning syndrome (Tako-Tsubo or stress cardiomyopathy): a mimic of acute myocardial infarction. Am Heart J. 2008;155(3):408-17.
[7] Bennett JR, McCarty D, Wilson CM, O'Neill F. Takotsubo cardiomyopathy: an uncommon cause of ST segment elevation in intensive care. Anaesthesia. 2007;62(3):279-81.
[8] Finsterer J, Wahbi K. CNS disease triggering Takotsubo stress cardiomyopathy. Int J Cardiol. 2014;177(2):322-9.
[9] Bybee KA, Kara T, Prasad A, Lerman A, Barsness GW, Wright RS, et al. Systematic review: transient left ventricular apical ballooning: a syndrome that mimics ST-segment elevation myocardial infarction. Ann Intern Med. 2004;141(11):858-65.
| Files | ||
| Issue | Vol 7 No 4 (2021): Autumn |
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| Section | Case Report(s) | |
| DOI | https://doi.org/10.18502/aacc.v7i4.7638 | |
| Keywords | ||
| Seizure Takotsubo cardiomyopathy Vasopressors | ||
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
How to Cite
1.
Khadka B, Khanal K. Takotsubo Cardiomyopathy as a Complication/Sequelae of Prolonged Refractory Seizure: A Case Report from Nepal. Arch Anesth & Crit Care. 2021;7(4):297-300.
